DEPLETION OF CYTOSOLIC PHOSPHOLIPASE A(2) IN BONE MARROW-DERIVED MACROPHAGES PROTECTS AGAINST LUNG CANCER PROGRESSION AND METASTASIS

Cancer progression and metastasis involves interactions between tumor cells and the tumor microenvironment (TME). We reported that mice deficient for cytosolic phospholipase A(2) (cPLA(2)-KO) are protected against the development of lung tumors. The goal of this study was to examine the role of cPLA...

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Autors principals: Weiser-Evans, Mary C.M., Wang, Xue-Qing, Amin, Jay, Van Putten, Vicki, Choudhary, Rashmi, Winn, Robert A., Scheinman, Robert, Simpson, Peter, Nemenoff, Raphael A.
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2653105/
https://ncbi.nlm.nih.gov/pubmed/19208832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-3766
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