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DEPLETION OF CYTOSOLIC PHOSPHOLIPASE A(2) IN BONE MARROW-DERIVED MACROPHAGES PROTECTS AGAINST LUNG CANCER PROGRESSION AND METASTASIS

Cancer progression and metastasis involves interactions between tumor cells and the tumor microenvironment (TME). We reported that mice deficient for cytosolic phospholipase A(2) (cPLA(2)-KO) are protected against the development of lung tumors. The goal of this study was to examine the role of cPLA...

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Dettagli Bibliografici
Autori principali: Weiser-Evans, Mary C.M., Wang, Xue-Qing, Amin, Jay, Van Putten, Vicki, Choudhary, Rashmi, Winn, Robert A., Scheinman, Robert, Simpson, Peter, Nemenoff, Raphael A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2653105/
https://ncbi.nlm.nih.gov/pubmed/19208832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-3766
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