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PTH-mediated regulation of Na(+)-K(+)-ATPase requires Src kinase-dependent ERK phosphorylation
Parathyroid hormone (PTH) inhibits Na(+)-K(+)-ATPase activity by serine phosphorylation of the α(1)-subunit through ERK-dependent phosphorylation and translocation of protein kinase Cα (PKCα). On the basis of previous studies, we postulated that PTH regulates sodium pump activity through Src kinase,...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Physiological Society
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2653102/ https://ncbi.nlm.nih.gov/pubmed/18550646 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00516.2007 |
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