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A Role for Calcium-Activated Adenylate Cyclase and Protein Kinase A in the Lens Src Family Kinase and Na,K-ATPase Response to Hyposmotic Stress

PURPOSE: Na,K-ATPase activity in lens epithelium is subject to control by Src family tyrosine kinases (SFKs). Previously we showed hyposmotic solution causes an SFK-dependent increase in Na,K-ATPase activity in the epithelium. Here we explored the role of cAMP in the signaling mechanism responsible...

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Publicat a:Invest Ophthalmol Vis Sci
Autors principals: Shahidullah, Mohammad, Mandal, Amritlal, Delamere, Nicholas A.
Format: Artigo
Idioma:Inglês
Publicat: The Association for Research in Vision and Ophthalmology 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6108779/
https://ncbi.nlm.nih.gov/pubmed/28863406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.17-21600
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