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Gap Junction Remodeling and Spironolactone-Dependent Reverse Remodeling in the Hypertrophied Heart

Pressure overload is a common pathological insult to the heart and the resulting hypertrophy is an independent risk factor for sudden cardiac death. Gap junction remodeling (GJR) has been described in hypertrophied hearts; however, a detailed understanding of the remodeling process and its effects o...

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Hlavní autoři: Qu, Jiaxiang, Volpicelli, Frank M., Garcia, Luis I., Sandeep, Nefthi, Zhang, Jie, Márquez-Rosado, Lucrecia, Lampe, Paul D., Fishman, Glenn I.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2652889/
https://ncbi.nlm.nih.gov/pubmed/19096029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.108.184044
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