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The ErbB inhibitors, trastuzumab and erlotinib, inhibit growth of vestibular schwannoma xenografts in nude mice: a preliminary study

OBJECTIVE: To determine the ability of ErbB inhibitors to reduce the growth of vestibular schwannoma (VS) xenografts. METHODS: VS xenografts were established in the interscapular fat pad in nude mice for 4 weeks. Initially, a small cohort of animals was treated with the ErbB2 inhibitor, trastuzumab,...

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Detalhes bibliográficos
Main Authors: Clark, J. Jason, Provenzano, Matthew, Diggelmann, Henry R., Xu, Ningyong, Hansen, Skylar S., Hansen, Marlan R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2652856/
https://ncbi.nlm.nih.gov/pubmed/18636037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MAO.0b013e31817f7398
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