Arsenic Exposure In utero Exacerbates Skin Cancer Response in Adulthood with Contemporaneous Distortion of Tumor Stem Cell Dynamics

Arsenic is a carcinogen with transplacental activity that can affect human skin stem cell population dynamics in vitro by blocking exit into differentiation pathways. Keratinocyte stem cells (KSC) are probably a key target in skin carcinogenesis. Thus, we tested the effects of fetal arsenic exposure...

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Bibliographic Details
Main Authors: Waalkes, Michael P., Liu, Jie, Germolec, Dori R., Trempus, Carol S., Cannon, Ronald E., Tokar, Erik J., Tennant, Raymond W., Ward, Jerrold M., Diwan, Bhalchandra A.
Format: Artigo
Language:Inglês
Published: 2008
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2652700/
https://ncbi.nlm.nih.gov/pubmed/18922899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-2099
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