High potency olfactory receptor agonists discovered by virtual high-throughput screening: molecular probes for receptor structure and olfactory function

The detection and discrimination of diverse chemical structures by the vertebrate olfactory system is accomplished by the recognition of odorous ligands by their cognate receptors. In the present study we used a computational high-throughput screening strategy to discover novel high affinity agonist...

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Detalhes bibliográficos
Main Authors: Triballeau, Nicolas, Van Name, Eric, Laslier, Guillaume, Cai, Diana, Paillard, Guillaume, Sorensen, Peter W., Hoffmann, Rémy, Bertrand, Hugues-Olivier, Ngai, John, Acher, Francine C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2652502/
https://ncbi.nlm.nih.gov/pubmed/19081373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2008.11.014
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