The carboxyl terminal trimer of procollagen I induces pro-metastatic changes and vascularization in breast cancer cells xenografts

BACKGROUND: The COOH terminal peptide of Pro-collagen type I (PICP, also called C3) is chemotactic for endothelial melanoma and breast cancer cells. PICP induces the expression of Metalloproteinases-2 and -9, of Vascular endothelial growth factor and of the chemokine CXCL-12 receptor CXCR4 in MDA MB...

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Detalhes bibliográficos
Main Authors: Visigalli, Davide, Palmieri, Daniela, Strangio, Antonella, Astigiano, Simonetta, Barbieri, Ottavia, Casartelli, Gianluigi, Zicca, Antonio, Manduca, Paola
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2652491/
https://ncbi.nlm.nih.gov/pubmed/19226458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-9-59
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