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Magnesium-Catalyzed Asymmetric Direct Aldol Addition of Ethyl Diazoacetate to Aromatic, Aliphatic, and α,β-Unsaturated Aldehydes

[Image: see text] Magnesium-catalyzed enantioselective aldol between ethyl diazoacetate and aromatic, aliphatic, and α,β-unsaturated aldehydes affords α-diazo-β-hydroxy-esters in high enantioselectivities. Aldol adducts resulting from this asymmetric transformation are versatile intermediates toward...

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Hlavní autoři: Trost, Barry M., Malhotra, Sushant, Freid, Benjamin A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2652472/
https://ncbi.nlm.nih.gov/pubmed/19191696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja809181m
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