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HMGA1 is a molecular determinant of chemoresistance to gemcitabine in pancreatic adenocarcinoma

HMGA1 proteins are architectural transcription factors that are overexpressed by pancreatic adenocarcinomas. We previously have shown that RNA interference targeting the HMGA1 gene may represent a potential chemosensitizing strategy in pancreatic adenocarcinoma cells (S Liau et al, J Gastrointest Su...

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Detalhes bibliográficos
Main Authors: Liau, Siong-Seng, Whang, Edward
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2652398/
https://ncbi.nlm.nih.gov/pubmed/18316571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-07-1450
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