The HMGA1-COX-2 axis: A key molecular pathway and potential target in pancreatic adenocarcinoma

CONTEXT: Although pancreatic cancer is a common, highly lethal malignancy, the molecular events that enable precursor lesions to become invasive carcinoma remain unclear. We previously reported that the high-mobility group A1 (HMGA1) protein is overexpressed in >90% of primary pancreatic cancers,...

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Detalhes bibliográficos
Main Authors: Hillion, Joelle, Smail, Shamayra S., Di Cello, Francescopaolo, Belton, Amy, Shah, Sandeep, Huso, Tait, Schuldenfrei, Andrew, Nelson, Dwella Moton, Cope, Leslie, Campbell, Nathaniel, Karikari, Collins, Aderinto, Abimbola, Maitra, Anirban, Huso, David L., Resar, Linda M. S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3466102/
https://ncbi.nlm.nih.gov/pubmed/22898640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pan.2012.05.005
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