Population-specific genetic variants important in susceptibility to cytarabine arabinoside cytotoxicity

Cytarabine arabinoside (ara-C) is an antimetabolite used to treat hematologic malignancies. Resistance is a common reason for treatment failure with adverse side effects contributing to morbidity and mortality. Identification of genetic factors important in susceptibility to ara-C cytotoxicity may a...

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Bibliografiske detaljer
Main Authors: Hartford, Christine M., Duan, Shiwei, Delaney, Shannon M., Mi, Shuangli, Kistner, Emily O., Lamba, Jatinder K., Huang, R. Stephanie, Dolan, M. Eileen
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2009
Fag:
Clinical Trials and Observations
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2652364/
https://ncbi.nlm.nih.gov/pubmed/19109566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-05-154302
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