The PN2-3 Domain of Centrosomal P4.1-associated Protein Implements a Novel Mechanism for Tubulin Sequestration

Microtubules are cytoskeletal components involved in multiple cell functions such as mitosis, motility, or intracellular traffic. In vivo, these polymers made of αβ-tubulin nucleate mostly from the centrosome to establish the interphasic microtubule network or, during mitosis, the mitotic spindle. C...

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Main Authors: Cormier, Anthony, Clément, Marie-Jeanne, Knossow, Marcel, Lachkar, Sylvie, Savarin, Philippe, Toma, Flavio, Sobel, André, Gigant, Benoît, Curmi, Patrick A.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2009
Teme:
Protein Structure and Folding
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2652345/
https://ncbi.nlm.nih.gov/pubmed/19131341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M808249200
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