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The Inhibitory Mechanism of Protein Synthesis by YoeB, an Escherichia coli Toxin

YoeB is a toxin encoded by the yefM-yoeB antitoxin-toxin operon in the Escherichia coli genome. Here we show that YoeB, a highly potent protein synthesis inhibitor, specifically blocks translation initiation. In in vivo primer extension experiments using two different mRNAs, a major band was detecte...

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Autors principals: Zhang, Yonglong, Inouye, Masayori
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2652283/
https://ncbi.nlm.nih.gov/pubmed/19124462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M808779200
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