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Mobilization of Lysosomal Calcium Regulates the Externalization of Phosphatidylserine during Apoptosis

A hallmark of apoptotic cells is the Ca(2+)-dependent appearance of phosphatidylserine (PS) at the cell surface as a result of its redistribution from the inner-to-outer plasma membrane leaflet. Although endoplasmic reticulum and mitochondrial Ca(2+) are known to participate in apoptosis, their role...

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Bibliografiske detaljer
Main Authors: Mirnikjoo, Banafsheh, Balasubramanian, Krishnakumar, Schroit, Alan J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2652277/
https://ncbi.nlm.nih.gov/pubmed/19126538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M805288200
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