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Niemann-Pick C1 Functions in Regulating Lysosomal Amine Content
Mutations in the late endosomal/lysosomal membrane protein Niemann-Pick C1 (NPC1) are known to cause a generalized block in retrograde vesicle-mediated transport, resulting in the hyper-accumulation of multiple lysosomal cargos. An important, yet often overlooked, category of lysosomal cargo include...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2528997/ https://ncbi.nlm.nih.gov/pubmed/18591242 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M803715200 |
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