Aldosterone increases K(Ca)1.1 (BK) channel-mediated colonic K(+) secretion

Mammalian K(+) homeostasis results from highly regulated renal and intestinal absorption and secretion, which balances the unregulated K(+) intake. Aldosterone is known to enhance both renal and colonic K(+) secretion. In mouse distal colon K(+) secretion occurs exclusively via luminal K(Ca)1.1 (BK)...

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Bibliographic Details
Main Authors: Sørensen, Mads V, Matos, Joana E, Sausbier, Matthias, Sausbier, Ulrike, Ruth, Peter, Praetorius, Helle A, Leipziger, Jens
Format: Artigo
Language:Inglês
Published: Blackwell Science Inc 2008
Subjects:
Renal and Endocrine
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2652187/
https://ncbi.nlm.nih.gov/pubmed/18617563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2008.156968
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