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N-Arachidonoyl l-Serine, a Putative Endocannabinoid, Alters the Activation of N-Type Ca(2+) Channels in Sympathetic Neurons

The effect of N-arachidonoyl l-serine (ARA-S), a recently discovered lipoamino acid found in the CNS, on N-type Ca(2+) channels of rat sympathetic ganglion neurons was determined using whole cell patch clamp. Application of ARA-S produced a rapid and reversible augmentation of Ca(2+) current that wa...

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Bibliographic Details
Main Authors: Guo, Juan, Williams, Damian J., Ikeda, Stephen R.
Format: Artigo
Language:Inglês
Published: American Physiological Society 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2652135/
https://ncbi.nlm.nih.gov/pubmed/18234973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.01204.2007
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