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Reassessing the Role of APOBEC3G in Human Immunodeficiency Virus Type 1 Infection of Quiescent CD4+ T-Cells

HIV-1 is restricted for infection of primary quiescent T-cells. After viral entry, reverse transcription is initiated but is not completed. Various hypotheses have been proposed for this cellular restriction including insufficient nucleotide pools and cellular factors, but none have been confirmed a...

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Библиографические подробности
Главные авторы: Kamata, Masakazu, Nagaoka, Yoshiko, Chen, Irvin S. Y.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2009
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2652112/
https://ncbi.nlm.nih.gov/pubmed/19300495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000342
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