APOBEC3F and APOBEC3G mRNA Levels Do Not Correlate with Human Immunodeficiency Virus Type 1 Plasma Viremia or CD4(+) T-Cell Count

APOBEC3F and APOBEC3G (hA3F and hA3G) are part of an innate mechanism of antiretroviral defense. The human immunodeficiency virus type 1 (HIV-1) accessory protein Vif targets both proteins for proteasomal degradation. Using mRNA from peripheral blood mononuclear cells of 92 HIV-infected subjects not...

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Autores principales: Cho, Soo-Jin, Drechsler, Henning, Burke, Ryan C., Arens, Max Q., Powderly, William, Davidson, Nicholas O.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2006
Materias:
Pathogenesis and Immunity
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1367163/
https://ncbi.nlm.nih.gov/pubmed/16439564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.80.4.2069-2072.2006
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