Helper T-Cell Responses and Clinical Activity of a Melanoma Vaccine With Multiple Peptides From MAGE and Melanocytic Differentiation Antigens

PURPOSE: A phase I/II trial was performed to evaluate the safety and immunogenicity of a novel melanoma vaccine comprising six melanoma-associated peptides defined as antigenic targets for melanoma-reactive helper T cells. Source proteins for these peptides include MAGE proteins, MART-1/MelanA, gp10...

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Bibliografiska uppgifter
Huvudupphovsmän: Slingluff, Craig L., Petroni, Gina R., Olson, Walter, Czarkowski, Andrea, Grosh, William W., Smolkin, Mark, Chianese-Bullock, Kimberly A., Neese, Patrice Y., Deacon, Donna H., Nail, Carmel, Merrill, Priscilla, Fink, Robyn, Patterson, James W., Rehm, Patrice K.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society of Clinical Oncology 2008
Ämnen:
Melanoma
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2652084/
https://ncbi.nlm.nih.gov/pubmed/18809608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2008.17.3161
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