Potential Excess Mortality in BRCA1/2 Mutation Carriers beyond Breast, Ovarian, Prostate, and Pancreatic Cancers, and Melanoma

BACKGROUND: Although the increase in risk of developing breast, ovarian, and prostate cancer in BRCA1 and BRCA2 mutation carriers has been studied extensively, its impact on mortality is not well quantified. Further, possible effect of BRCA mutations on non-cancer mortality risk has not been examine...

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Detalhes bibliográficos
Main Authors: Mai, Phuong L., Chatterjee, Nilanjan, Hartge, Patricia, Tucker, Margaret, Brody, Lawrence, Struewing, Jeffery P., Wacholder, Sholom
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2652075/
https://ncbi.nlm.nih.gov/pubmed/19277124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0004812
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