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Potential Excess Mortality in BRCA1/2 Mutation Carriers beyond Breast, Ovarian, Prostate, and Pancreatic Cancers, and Melanoma

BACKGROUND: Although the increase in risk of developing breast, ovarian, and prostate cancer in BRCA1 and BRCA2 mutation carriers has been studied extensively, its impact on mortality is not well quantified. Further, possible effect of BRCA mutations on non-cancer mortality risk has not been examine...

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Hlavní autoři: Mai, Phuong L., Chatterjee, Nilanjan, Hartge, Patricia, Tucker, Margaret, Brody, Lawrence, Struewing, Jeffery P., Wacholder, Sholom
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2652075/
https://ncbi.nlm.nih.gov/pubmed/19277124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0004812
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