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Tumor Necrosis Factor-like Weak Inducer of Apoptosis (TWEAK) activates proinflammatory signaling pathways and gene expression through the activation of TGF-beta activated kinase 1

TWEAK is a relatively recently identified proinflammatory cytokine which functions through binding to Fn14 receptor in target cells. Although TWEAK has been shown to modulate several biological responses, the TWEAK-induced signaling pathways remain poorly understood. In this study, we tested the hyp...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kumar, Mukesh, Makonchuk, Denys Y., Li, Hong, Mittal, Ashwani, Kumar, Ashok
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2652039/
https://ncbi.nlm.nih.gov/pubmed/19201899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0803357
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