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Proinflammatory Cytokine Tumor Necrosis Factor (TNF)-like Weak Inducer of Apoptosis (TWEAK) Suppresses Satellite Cell Self-renewal through Inversely Modulating Notch and NF-κB Signaling Pathways

Satellite cell self-renewal is an essential process to maintaining the robustness of skeletal muscle regenerative capacity. However, extrinsic factors that regulate self-renewal of satellite cells are not well understood. Here, we demonstrate that TWEAK cytokine reduces the proportion of Pax7(+)/Myo...

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Detalhes bibliográficos
Main Authors: Ogura, Yuji, Mishra, Vivek, Hindi, Sajedah M., Kuang, Shihuan, Kumar, Ashok
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3853267/
https://ncbi.nlm.nih.gov/pubmed/24151074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.517300
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