ロード中...
hSMG-1 and ATM sequentially and independently regulate the G1 checkpoint during oxidative stress
Genotoxic stress activates the phosphatidylinositol 3-kinase like kinases (PIKKs) that phosphorylate proteins involved in cell cycle arrest, DNA repair, and apoptosis. Previous work showed that the PIKK ataxia telangiectasia mutated (ATM) but not ATR (ATM and Rad3-related) phosphorylates p53 (Ser15)...
保存先:
| 主要な著者: | , , , , |
|---|---|
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2008
|
| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2651885/ https://ncbi.nlm.nih.gov/pubmed/18332866 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2008.48 |
| タグ: |
タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!
|