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Positioning of subdomain IIId and apical loop of domain II of the hepatitis C IRES on the human 40S ribosome
The 5′-untranslated region of the hepatitis C virus (HCV) RNA contains a highly structured motif called IRES (Internal Ribosome Entry Site) responsible for the cap-independent initiation of the viral RNA translation. At first, the IRES binds to the 40S subunit without any initiation factors so that...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Oxford University Press
2009
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2651777/ https://ncbi.nlm.nih.gov/pubmed/19129232 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn1026 |
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