Positioning of subdomain IIId and apical loop of domain II of the hepatitis C IRES on the human 40S ribosome

The 5′-untranslated region of the hepatitis C virus (HCV) RNA contains a highly structured motif called IRES (Internal Ribosome Entry Site) responsible for the cap-independent initiation of the viral RNA translation. At first, the IRES binds to the 40S subunit without any initiation factors so that...

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Main Authors: Babaylova, Elena, Graifer, Dmitri, Malygin, Alexey, Stahl, Joachim, Shatsky, Ivan, Karpova, Galina
格式: Artigo
語言:Inglês
出版: Oxford University Press 2009
主題:
Molecular Biology
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2651777/
https://ncbi.nlm.nih.gov/pubmed/19129232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn1026
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