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The structure of C2b, a fragment of complement component C2 produced during C3 convertase formation

The second component of complement (C2) is a multi-domain serine protease that provides catalytic activity for the C3 and C5 convertases of the classical and lectin pathways of human complement. The formation of these convertases requires the Mg(2+)-dependent binding of C2 to C4b and the subsequent...

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Detalhes bibliográficos
Main Authors: Krishnan, Vengadesan, Xu, Yuanyuan, Macon, Kevin, Volanakis, John E., Narayana, Sthanam V. L.
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2651757/
https://ncbi.nlm.nih.gov/pubmed/19237749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S0907444909000389
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