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Mechanistic Insight into the Role of Transition-State Stabilization in Cyclophilin A
[Image: see text] Peptidyl prolyl cis−trans isomerases (PPIases) are ubiquitous enzymes in biology that catalyze the cis−trans isomerization of the proline imide peptide bond in many cell signaling pathways. The local change of the isomeric state of the prolyl peptide bond acts as a switching mechan...
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| 主要な著者: | , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Chemical Society
2008
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| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2651649/ https://ncbi.nlm.nih.gov/pubmed/19128175 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja806146g |
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