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Ribozymes: Analytical Solution of the One-substrate, Two-intermediate Reversible Scheme for Enzyme Reactions

The paper presents a kinetic analysis of a reversible enzymatic reaction S⇄P involving two intermediate compounds under the condition [E](0) ≫ [S](0) + [P](0). For the case of mono-exponential behavior, we derive an equation for k(obs) as a function of [E](0), which emphasizes the pitfalls of oversi...

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Detalhes bibliográficos
Main Authors: Toti, Paolo, Sbordone, Ludovico, Sbordone, Carolina, Bauer, Carlo
Formato: Artigo
Idioma:Inglês
Publicado em: Kluwer Academic Publishers 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2651541/
https://ncbi.nlm.nih.gov/pubmed/19669435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10867-006-9030-z
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