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In Silico Simulation of Corticosteroids Effect on an NFkB- Dependent Physicochemical Model of Systemic Inflammation

BACKGROUND: During the onset of an inflammatory response signaling pathways are activated for “translating” extracellular signals into intracellular responses converging to the activation of nuclear factor (NF)-kB, a central transcription factor in driving the inflammatory response. An inadequate co...

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Detalhes bibliográficos
Main Authors: Foteinou, Panagiota T., Calvano, Steve E., Lowry, Stephen F., Androulakis, Ioannis P.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2651450/
https://ncbi.nlm.nih.gov/pubmed/19274080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0004706
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