Nitroglycerine causes mitochondrial reactive oxygen species production: In vitro mechanistic insights

BACKGROUND: Nitroglycerine (GTN) is an organic nitrate that has been used for more than 100 years. Despite its widespread clinical use, several aspects of the pharmacology of GTN remain elusive. In a recent study, the authors of the present study showed that GTN causes opening of the mitochondrial p...

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Main Authors: Gori, Tommaso, Daiber, Andreas, Di Stolfo, Giuseppe, Sicuro, Silvia, Dragoni, Saverio, Lisi, Monica, M¨nzel, Thomas, Forconi, Sandro, Parker, John D
Format: Artigo
Sprog:Inglês
Udgivet: Pulsus Group Inc 2007
Fag:
Basic Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2651423/
https://ncbi.nlm.nih.gov/pubmed/17932576
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