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Tat acetylation modulates assembly of a viral-host RNA–protein transcription complex
HIV-1 Tat enhances viral transcription elongation by forming a ribonucleoprotein complex with transactivating responsive (TAR) RNA and P-TEFb, an elongation factor composed of cyclin T1 (CycT1) and Cdk9 that phosphorylates the C-terminal domain of RNA polymerase II. Previous studies have shown that...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
2009
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2651313/ https://ncbi.nlm.nih.gov/pubmed/19223581 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0900012106 |
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