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Site-specific chemical modification of recombinant proteins produced in mammalian cells by using the genetically encoded aldehyde tag
The properties of therapeutic proteins can be enhanced by chemical modification. Methods for site-specific protein conjugation are critical to such efforts. Here, we demonstrate that recombinant proteins expressed in mammalian cells can be site-specifically modified by using a genetically encoded al...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2651276/ https://ncbi.nlm.nih.gov/pubmed/19202059 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0807820106 |
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