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Crystal structure of the eIF4A–PDCD4 complex

Tumor suppressor programmed cell death protein 4 (PDCD4) inhibits the translation initiation factor eIF4A, an RNA helicase that catalyzes the unwinding of secondary structure at the 5′-untranslated region of mRNAs and controls the initiation of translation. Here, we determined the crystal structure...

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Detalhes bibliográficos
Main Authors: Chang, Jeong Ho, Cho, Yong Hyun, Sohn, Sun Young, Choi, Jung Min, Kim, Ahreum, Kim, Young Chang, Jang, Sung Key, Cho, Yunje
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2651268/
https://ncbi.nlm.nih.gov/pubmed/19204291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0808275106
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