CXCL14 is an autocrine growth factor for fibroblasts and acts as a multi-modal stimulator of prostate tumor growth

This study explored the role of secreted fibroblast-derived factors in prostate cancer growth. Analyses of matched normal and tumor tissue revealed up-regulation of CXCL14 in cancer-associated fibroblasts of a majority of prostate cancer. Fibroblasts over-expressing CXCL14 promoted the growth of pro...

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Hauptverfasser: Augsten, Martin, Hägglöf, Christina, Olsson, Eleonor, Stolz, Claudia, Tsagozis, Panagiotis, Levchenko, Tetyana, Frederick, Mitchell J., Borg, Åke, Micke, Patrick, Egevad, Lars, Östman, Arne
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2009
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2651265/
https://ncbi.nlm.nih.gov/pubmed/19218429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0813144106
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