Nicotinamide mononucleotide synthetase is the key enzyme for an alternative route of NAD biosynthesis in Francisella tularensis

Enzymes involved in the last 2 steps of nicotinamide adenine dinucleotide (NAD) cofactor biosynthesis, which catalyze the adenylylation of the nicotinic acid mononucleotide (NaMN) precursor to nicotinic acid dinucleotide (NaAD) followed by its amidation to NAD, constitute promising drug targets for...

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Detalhes bibliográficos
Main Authors: Sorci, Leonardo, Martynowski, Dariusz, Rodionov, Dmitry A., Eyobo, Yvonne, Zogaj, Xhavit, Klose, Karl E., Nikolaev, Evgeni V., Magni, Giulio, Zhang, Hong, Osterman, Andrei L.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2651253/
https://ncbi.nlm.nih.gov/pubmed/19204287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0811718106
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