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Practical Synthesis of 3β-Amino-5-Cholestene and Related 3β-Halides Involving i-Steroid and Retro-i-Steroid Rearrangements

[Image: see text] Derivatives of 3β-amino-5-cholestene (3β-cholesterylamine) are of substantial interest as cellular probes and have potential medicinal applications. However, existing syntheses of 3β-amino-5-cholestene are of limited preparative utility. We report here a practical method for the st...

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Main Authors: Sun, Qi, Cai, Sutang, Peterson, Blake R.
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2651230/
https://ncbi.nlm.nih.gov/pubmed/19115840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol802343z
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