Endothelial Cell PECAM-1 Promotes Atherosclerotic Lesions in Areas of Disturbed Flow in ApoE-Deficient Mice

OBJECTIVE: Platelet endothelial cell adhesion molecule-1 (PECAM-1, CD31) has recently been shown to form an essential element of a mechanosensory complex that mediates endothelial responses to fluid shear stress. The aim of this study was to determine the in vivo role of PECAM-1 in atherosclerosis....

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Detalhes bibliográficos
Main Authors: Harry, Brian L., Sanders, John M., Feaver, Ryan E., Lansey, Melissa, Deem, Tracy L., Zarbock, Alexander, Bruce, Anthony C., Pryor, Andrew W., Gelfand, Bradley D., Blackman, Brett R., Schwartz, Martin A., Ley, Klaus
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2651147/
https://ncbi.nlm.nih.gov/pubmed/18688018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.108.164707
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