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Evolution of the Randomized Controlled Trial in Oncology Over Three Decades

PURPOSE: The randomized controlled trial (RCT) is the gold standard for establishing new therapies in clinical oncology. Here we document changes with time in design, sponsorship, and outcomes of oncology RCTs. METHODS: Reports of RCTs evaluating systemic therapy for breast, colorectal (CRC), and no...

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Detalhes bibliográficos
Main Authors: Booth, Christopher M., Cescon, David W., Wang, Lisa, Tannock, Ian F., Krzyzanowska, Monika K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Clinical Oncology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2651075/
https://ncbi.nlm.nih.gov/pubmed/18955452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2008.16.5456
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