Residual DNA methylation at remission is prognostic in adult Philadelphia chromosome–negative acute lymphocytic leukemia

Pretreatment aberrant DNA methylation patterns are stable at time of relapse in acute lymphocytic leukemia (ALL). We hypothesized that the detection of residual methylation alterations at the time of morphologic remission may predict for worse prognosis. We developed a real-time bisulfite polymerase...

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Detaylı Bibliyografya
Asıl Yazarlar: Yang, Hui, Kadia, Tapan, Xiao, Lianchun, Bueso-Ramos, Carlos E., Hoshino, Koyu, Thomas, Deborah Ann, O'Brien, Susan, Jabbour, Elias, Pierce, Sherry, Rosner, Gary L., Kantarjian, Hagop M., Garcia-Manero, Guillermo
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society of Hematology 2009
Konular:
Clinical Trials and Observations
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2651008/
https://ncbi.nlm.nih.gov/pubmed/19109226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-02-141002
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