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Systemic microdystrophin gene delivery improves skeletal muscle structure and function in old dystrophic mdx mice

Restoring dystrophin expression in the muscles of patients with Duchenne muscular dystrophy (DMD) may halt or reverse the degenerative wasting and weakness that causes premature death. However, the therapeutic efficacy of an intervention may be limited by the extent of disease progression prior to t...

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Bibliografiska uppgifter
Huvudupphovsmän: Gregorevic, Paul, Blankinship, Michael J., Allen, James M., Chamberlain, Jeffrey S.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2008
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2650831/
https://ncbi.nlm.nih.gov/pubmed/18334986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2008.28
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