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Systemic microdystrophin gene delivery improves skeletal muscle structure and function in old dystrophic mdx mice

Restoring dystrophin expression in the muscles of patients with Duchenne muscular dystrophy (DMD) may halt or reverse the degenerative wasting and weakness that causes premature death. However, the therapeutic efficacy of an intervention may be limited by the extent of disease progression prior to t...

詳細記述

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書誌詳細
主要な著者: Gregorevic, Paul, Blankinship, Michael J., Allen, James M., Chamberlain, Jeffrey S.
フォーマット: Artigo
言語:Inglês
出版事項: 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2650831/
https://ncbi.nlm.nih.gov/pubmed/18334986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2008.28
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