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Systemic microdystrophin gene delivery improves skeletal muscle structure and function in old dystrophic mdx mice
Restoring dystrophin expression in the muscles of patients with Duchenne muscular dystrophy (DMD) may halt or reverse the degenerative wasting and weakness that causes premature death. However, the therapeutic efficacy of an intervention may be limited by the extent of disease progression prior to t...
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主要な著者: | , , , |
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フォーマット: | Artigo |
言語: | Inglês |
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2008
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オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2650831/ https://ncbi.nlm.nih.gov/pubmed/18334986 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2008.28 |
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