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Systemic microdystrophin gene delivery improves skeletal muscle structure and function in old dystrophic mdx mice

Restoring dystrophin expression in the muscles of patients with Duchenne muscular dystrophy (DMD) may halt or reverse the degenerative wasting and weakness that causes premature death. However, the therapeutic efficacy of an intervention may be limited by the extent of disease progression prior to t...

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Bibliografski detalji
Glavni autori: Gregorevic, Paul, Blankinship, Michael J., Allen, James M., Chamberlain, Jeffrey S.
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2650831/
https://ncbi.nlm.nih.gov/pubmed/18334986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2008.28
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