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Activation of Ribosomal RNA Transcription by Hepatitis C Virus Involves Upstream Binding Factor Phosphorylation Via Induction of Cyclin D1
Hepatitis C virus (HCV) causes chronic infection in humans leading to liver cirrhosis and hepatocellular carcinoma. Ribosomal RNA transcription, catalyzed by RNA polymerase I (Pol I), plays a critical role in ribosome biogenesis and changes in Pol I transcription rate are associated with profound al...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2650774/ https://ncbi.nlm.nih.gov/pubmed/19223538 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-3468 |
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