Suppressive activity of tiotropium bromide on matrix metalloproteinase production from lung fibroblasts in vitro

BACKGROUND: Chronic obstructive pulmonary disease (COPD) is characterized by airway remodeling with an accumulation of inflammatory cells. There is also increasing evidence that metalloproteinases (MMPs) may contribute to the pathogenesis of COPD, but the influence of agents that used for the treatm...

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Detalhes bibliográficos
Main Authors: Asano, Kazuhito, Shikama, Yusuke, Shibuya, Yasuhiro, Nakajima, Hiroaki, Kanai, Ken-ichi, Yamada, Naohiro, Suzaki, Harumi
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2008
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2650607/
https://ncbi.nlm.nih.gov/pubmed/19281093
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