Suppression of Matrix Metalloproteinase Production in Nasal Fibroblasts by Tranilast, an Antiallergic Agent, In Vitro

Allergic rhinitis is an inflammatory disease characterized by nasal wall remodeling with intense infiltration of eosinophils and mast cells/basophils. Matrix metalloproteinases (MMPs), MMP-2 and MMP-9, are the major proteolytic enzymes that induce airway remodeling. These enzymes are also important...

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Detalhes bibliográficos
Main Authors: Shimizu, Toshiyuki, Kanai, Kenichi, Asano, Kazuhito, Hisamitsu, Tadashi, Suzaki, Harumi
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2005
Assuntos:
Research Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1526475/
https://ncbi.nlm.nih.gov/pubmed/16106101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/MI.2005.150
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