Robust Antiviral Efficacy upon Administration of a Nucleoside Analog to Hepatitis C Virus-Infected Chimpanzees

Hepatitis C virus (HCV) infects an estimated 170 million individuals worldwide and is associated with an increased incidence of liver fibrosis, cirrhosis, and hepatocellular carcinoma. Currently approved therapies to treat HCV infection consist of combinations of pegylated alpha interferon and ribav...

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Detalhes bibliográficos
Main Authors: Carroll, Steven S., Ludmerer, Steven, Handt, Larry, Koeplinger, Kenneth, Zhang, Nanyan Rena, Graham, Donald, Davies, Mary-Ellen, MacCoss, Malcolm, Hazuda, Daria, Olsen, David B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2650549/
https://ncbi.nlm.nih.gov/pubmed/19075052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01032-08
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